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Archive for the ‘Clinical review’ Category

Clinical Review, by: L Fuccio, research fellow et al, Department of Internal Medicine and Gastroenterology, University of Bologna.
BMJ, 15 September 2008

The prevalence of H pylori varies widely and is about 50% in international population studies. Helicobacter pylori is one of the most common human infections, and about half of the world’s population carries this organism. [...]

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By: Charles Musters, specialist registrar in perinatal psychiatry, Elizabeth McDonald, consultant in perinatal psychiatry and Ian Jones, senior lecturer in perinatal psychiatry.
BMJ, 8 August 2008

Postnatal depression occurs after 13% of births.
The nature of the puerperal trigger is still unknown, but several psychological, social, and biological factors probably play a part. Genetic factors have been implicated
A [...]

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Thyroxine structure
By: Bijay Vaidya, consultant endocrinologist and honorary senior clinical lecturer and Simon H S Pearce, professor of endocrinology and honorary consultant physician, Newcastle upon Tyne.
BMJ 28 July 2008
Hypothyroidism is one of the commonest chronic disorders in Western populations. In the United Kingdom, the annual incidence of primary hypothyroidism in women is 3.5 per [...]

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BMJ, 17 July 2008
By: John B Winer, consultant neurologist, University Hospital Birmingham, UK.
What are the clinical features?

All types of Guillain-Barré syndrome present with acute neuropathy, defined as: progressive onset of limb weakness that reaches its worst within four weeks.
Typically there are sensory symptoms but few sensory signs.
Reflexes are usually lost early in the illness.
The [...]

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BMJ 2008;336:1062-1066 (10 May).
Clinical Review
By: J R Fraser Cummings, specialist registrar, Satish Keshav, consultant gastroenterologist, Simon P L Travis, consultant gastroenterologist (Gastroenterology Unit, John Radcliffe Hospital, Oxford)
Summary points

Biological therapies have radically changed the management of Crohn’s disease but must be used judiciously with great awareness of possible adverse events
Treatment strategies for the disease are [...]

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BMJ 2008;336:416-417 (23 February).
As calls to end drug companies’ direct sponsorship of doctors’ education echo round the world, an investigation in Australia reveals sponsor involvement in the education of thousands of general practitioners, writes Ray Moynihan, conjoint lecturer, University of Newcastle, New South Wales, and visiting editor, BMJ

Harvard professor David Blumenthal, an internationally [...]

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BMJ 2008;336:658-662 (22 March),
Clinical Review;
By: Christopher J McDermott, clinical senior lecturer and honorary consultant neurologist, Pamela J Shaw, professor, University of Sheffield.
Summary points

Motor neurone disease is relatively uncommon, with an annual incidence of 2 in 100 000; general practitioners may expect to see one or two cases during their career.

The cause of motor neurone disease [...]

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BMJ 2008;336:532-534 (8 March)(published 27 February 2008)
By: Jeanne Lenzer, medical investigative journalist, New York.

New generation antidepressants aren’t all they’re cracked up to be.
That seems to be the central message in the meta-analysis published this week by Irving Kirsch and colleagues in PLoS-Medicine, and it was this message that made the headlines.
Kirsch’s conclusion follows on the [...]

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BMJ 2008; (16 February).
Practice by: Dr Rebecca Greenhalgh, radiology specialist registrar et al, University College Hospital, London.

Imaging plays an important role in elucidating the cause of anal pain when the diagnosis is not clinically apparent.
Endoanal ultrasound is an increasingly available, relatively inexpensive, quick and safe technique providing high resolution images of the anal sphincter [...]

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BMJ 2008;336:107-108 (19 January),

More than 1.2 million women and men worldwide are diagnosed with breast cancer each year. In 2007, the 20 year survival rate for breast cancer will be greater than the five year survival rate 30 years ago.

Breast cancer is now recognised as a chronic disease that can recur even after 20-30 [...]

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